Name:

Epstein-Barr Virus Antibody Panel, IgG and IgM

Alternate Name:

EBV VCA IgG and EBV VCA IgM

Test Code:

EBVAB

Dept:

Chemistry

SPECIMEN COLLECTION REQUIREMENTS

Collection Container:

SST

Specimen:

Serum

Transport Temperature:

Room Temperature

Specimen Volume:

Preferred Volume: 1 mL; Minimum Volume: 0.5 mL

Also Acceptable:

Red Top Tube

TECHNICAL SPECIFICATIONS

Performed:

Monday - Friday

Reported:

Same Day

Methodology:

Multiplex Flow Immunoassay

CPT:

IgG: 86665

IgM: 86665

LOINC:

IgG: 24114-1

IgM: 24115-8

Stability:

Refrigerated: 7 Days; Frozen: 30 Days

Reference Range:

EBV VCA IgG Interpretation:

≤0.8 AI                   NEGATIVE              

Absence of detectable VCA IgG antibodies.  If exposure to Epstein-Barr virus is suspected despite a negative finding, a second sample should be collected and tested no less than one to two weeks later.

0.9-1.0 AI               EQUIVOCAL          

A second sample should be collected and retested no less than one to two weeks later.

≥1.1 AI                   POSITIVE               

Presence of detectable VCA IgG antibodies.  A positive result indicates current or past exposure to Epstein-Barr virus.

EBV VCA IgM Interpretation:

≤0.8 AI                   NEGATIVE              

Absence of detectable VCA IgM antibodies.  If exposure to Epstein-Barr virus is suspected despite a negative finding, a second sample should be collected and tested no less than one to two weeks later.

0.9-1.0 AI               EQUIVOCAL          

A second sample should be collected and retested no less than one to two weeks later.

≥1.1 AI                   POSITIVE               

Presence of detectable VCA IgM antibodies.  Specific IgM antibodies are usually detected in patients with recent primary infection and may be found in patients with reactivated infections.  Other EBV serology assays should be performed to confirm EBV-associated infectious mononucleosis.