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Test Code FACTN F-Actin (Smooth Muscle) Antibody (IgG)

Important Note

Test performed at Quest Diagnostics.  Click on link below for collection requirements:

 

http://www.questdiagnostics.com/testcenter/TestDetail.action?ntc=15043

 

Specimen Volume

Preferred: 0.5 mL Serum

Minimum: 0.25 mL Serum

Preferred Specimen

SST (Red Top Acceptable)

Transport

Routine courier pick-up

Department

Quest Diagnostics Nichols Institute

Methodology

Enzyme Linked Immunosorbent Immunoassay (ELISA)

STAT Turn-around Time

N/A

Routine Turn-around Time

3-5 days

Specimen Stability

Ambient: 14 Days

Refrigerated: 14 Days

Frozen: 30 Days

Reference Ranges

<20 U - Negative

≥20 U - Positive 

Antibodies recognizing actin are the main component of smooth muscle antibodies associated with autoimmune liver disease. Actin antibodies are found in approximately 75% of patients with autoimmune hepatitis (AIH) type 1, approximately 65% of patients with autoimmune cholangitis, approximately 30% of patients with primary biliary cirrhosis, and approximately 2% of healthy people. High values are closely correlated with AIH type 1.