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Test Code MSQSA Maternal Screen, AFP, Quad

Important Note

Second-trimester screening test for trisomy 21 (Down syndrome), trisomy 18, and open neural tube defects.

Submit with Order: Patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient was diabetic at the time of conception, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a trisomy, if the patient is currently smoking, if the patient is taking valproic acid or carbamazepine (Tegretol), if this is a repeat sample, and the age of the egg donor if in vitro fertilization.

Specimen Volume

3 mL

Preferred Specimen:

Serum from Serum Separator Tube (SST) or Plain Red.

Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. The recommended time for maternal serum screening is 16 to 18 weeks gestation.

Specimen Handling Instructions

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an aliquot tube. (Min: 1 mL)

Transport

Routine courier pick-up

Cutoff Time

None

Performing Laboratory

ARUP Laboratories

Methodology

Quantitative Chemiluminescent Immunoassay (CLIA)

STAT TAT

N/A

Routine Turn-around Time

Performed Daily

Report available: 2-3 days

Interpretive Data

Refer to report

CPT Codes

81511

LOINC Codes

1834-1

11778-8

35738-4

23883-2

20450-3

49586-1

19151-0

21299-3

8670-2

21484-1

11878-6

21612-7

2250-9

20466-9

32435-0

64234-8

11526-1

19080-1

20465-1

18185-9

29463-7

44877-9