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Mayo Clinic Laboratories

Test Code POLAB Poliovirus (Types 1, 3) Antibodies

Specimen Collection Requirements

1 mL serum from a Serum Separator Tube (SST) or Plain Red.

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an aliquout Tube. (Min: 0.2 mL)

Transport Temperature

Refrigerated

Methodology

Semi-Quantitative Serum Neutralization

Turn Around Time

Performed Monday-Friday

Turnaround Time: 7-13 days

Reference Range

Less than 1:10 No detectable poliovirus antibodies.
1:10 or greater Antibody to poliovirus detected, which may represent prior immunization or current or past infection.

Interpretive Data

The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against the other type.

Reference interval applies to Poliovirus Antibodies Types 1 and 3.