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Test Code TACPK Tacrolimus, Peak, Blood

Secondary ID

88157

Useful For

Assessment of postdosing (peak) blood tacrolimus concentrations

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Tacrolimus, Peak, B

Specimen Type

Whole Blood EDTA


Ordering Guidance


This test is for specimens collected during a peak period. For specimens collected at trough, order TAKRO / Tacrolimus, Blood.



Necessary Information


Date of last dose, time of last dose, and dosage information are required.



Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions:

1. Do not centrifuge.

2. Send whole blood specimen in original tube. Do not aliquot.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reject Due To

Gross hemolysis OK
Gros lipemia OK
Gross icterus OK
Clotted specimen Reject

Reference Values

5.0-30.0 ng/mL

 

Target steady-state trough concentrations vary depending on the type of transplant, concomitant immunosuppression, clinical/institutional protocols, and time posttransplant. Results should be interpreted in conjunction with this clinical information and any physical signs or symptoms of rejection or toxicity.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80197

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TACPK Tacrolimus, Peak, B 59822-7

 

Result ID Test Result Name Result LOINC Value
88157 Tacrolimus, Peak, B 59822-7
DAT7 Date of last dose 29742-4
TM01 Time of last dose 29637-6
DOSE1 Dose, mg 32594-4

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.