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Test Code TPPA Syphilis Antibody, Treponema pallidum Particle Agglutination, Serum

Reporting Name

Syphilis Ab by TP-PA, S

Useful For

An aid to resolve discrepant results between screening treponemal and non-treponemal assays

 

This test is not recommended for general screening purposes for syphilis.

 

This test should not be used to evaluate response to therapy.

 

This test is not intended for medical-legal use.

Testing Algorithm

For more information see Syphilis Serology Algorithm.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Ordering Guidance


This assay is recommended by the Centers for Disease Control and Prevention for sera testing positive by a screening treponemal assay and negative by rapid plasma reagin (RPR). The results of this assay assist in determining whether the results of a screening treponemal test are truly or falsely positive.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values

Negative

Day(s) Performed

Monday through Friday

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86780

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TPPA Syphilis Ab by TP-PA, S 24312-1

 

Result ID Test Result Name Result LOINC Value
61480 Syphilis Ab by TP-PA, S 24312-1

Special Instructions

Report Available

Same day/1 to 4 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Method Name

Particle Agglutination

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.