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Test Code TTG Tissue Transglutaminase Ab, IgA, Serum

Specimen Collection Requirements

Alt Name: Anti-TTG, TGTA, tTG, tTGA, Replaces Endomysial Antibody Test
Dept: Chemistry
SPECIMEN COLLECTION REQUIREMENTS
Collection Container:

SST

Specimen: Serum
Transport Temperature: Frozen
Specimen Volume: Preferred Volume: 1 mL; Minimum Volume: 0.5 mL
Also Acceptable: Red Top Tube
TECHNICAL SPECIFICATIONS
Performed: Tuesdays and Thursdays
Reported: Tuesdays and Thursdays
Methodology: Fluoroenzymeimmunoassay (ImmunoCAP)
CPT: 83516
LOINC: 46128-5
Stability: Frozen Recommended; Refrigerated: 14 Days
Reference Range:

Negative: <7 U/mL

Equivical: 7-10 U/mL

Positive: >10 U/mL

Notes: Anti-endomysial antibodies (EMA) are highly specific and sensitive markers for Celiac Disease. Recently the specific endomysial antigen has been identified as the protein crosslinking enzyme known as tissue transglutaminase (tTG). Detection of these antibodies is an aid in diagnosis of certain gluten sensitive enteropathies such as Celiac Disease and Dermatitis Herpetiformis.